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Effective interventions in overweight or obese young children: systematic review and meta-analysis
Esther van Hoek1, Edith J M Feskens, Laura I Bouwman
11 Department of Pediatrics, Gelderse Vallei Hospital , Ede, The Netherlands .
Insights
Multicomponent treatment programs combining diet, physical activity, and behavioral therapy are most effective for treating overweight young children. Moderate to high intensity programs showed the largest improvements in BMI z-score.
Area of Science:
- Pediatric Obesity Research
- Public Health Interventions
- Evidence-Based Medicine
Background:
- Effectiveness of childhood obesity treatment programs varies.
- Key characteristics of successful interventions remain unclear.
- Systematic review and meta-analysis to evaluate treatment effectiveness.
Purpose of the Study:
- To systematically review and meta-analyze the effectiveness of treatment programs for overweight and obese young children.
- To identify characteristics of effective interventions for pediatric obesity.
Main Methods:
- Comprehensive literature search of PubMed, Embase, Web of Science, and PsycINFO databases up to April 2012.
- Inclusion criteria: studies on overweight/obese children (mean age 3-8 years) reporting BMI z-score change.
- Random-effects model meta-analysis used to pool data from eligible studies.
Main Results:
- 27 articles were included, with 11 studies (1015 participants) eligible for meta-analysis.
- High heterogeneity observed in pooled intervention effects.
- Subgroup analysis revealed multicomponent programs (diet, physical activity, behavioral therapy) of moderate/high intensity showed the largest BMI z-score reduction (-0.46).
Conclusions:
- Multicomponent treatment programs, particularly those of moderate to high intensity, show promise for effectively treating overweight young children.
- Further research with larger sample sizes is warranted to confirm these findings.
Background:
Treatment programs for overweight and obese young children are of variable effectiveness, and the characteristics of effective programs are unknown. In this systematic review with meta-analysis, the effectiveness of treatment programs for these children is summarized.
Methods:
PubMed, Embase, Web of Science, and PsycINFO databases were searched up to April 2012. Articles reporting the effect of treatment on the body weight of overweight or obese children with a mean age in the range of 3-<8 years are included. Studies reporting the change in BMI z-score with standard error were included in a meta-analysis. For this purpose, a random-effects model was used.
Results:
The search identified 11,250 articles, of which 27 were included in this review. Eleven studies, including 20 treatment programs with 1015 participants, were eligible for the meta-analysis. The pooled intervention effect showed high heterogeneity; therefore, subgroup analysis was performed. Subgroup analysis showed that program intensity and used components partly explained the heterogeneity. The subgroup with two studies using multicomponent treatment programs (combining dietary and physical activity education and behavioral therapy) of moderate or high intensity showed the largest pooled change in BMI z-score (-0.46; I2, 0%).
Conclusion:
Although the subgroup multicomponent treatment programs of moderate to high intensity contained only two studies, these treatment programs appeared to be most effective in treating overweight young children.
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