Related Experiment Video
Updated: Jan 20, 2026

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
Published on: May 26, 2023
Changes in maximum expiratory flow-volume curve configuration after treatment with inhaled corticosteroids
J Kraan1, T W van der Mark, G H Koëter
1Department of Lung Disease, University Hospital, Groningen, The Netherlands.
Abstract:
The present study reports the changes in configuration of maximal flow-volume curves after eight weeks' treatment with inhaled corticosteroids in 14 asthmatic patients. The configuration was compared with that seen after bronchodilatation following inhalation of a single dose of ipratropium bromide. After inhaled corticosteroids the shape of the flow-volume curves was less bowed toward the volume axis, whereas the shape of the flow-volume curves after inhalation of ipratropium bromide showed no significant change. A significant correlation was observed between the decrease in blood eosinophil cell count and the straightening of the flow-volume curves, quantitatively expressed as shape factor and slope ratio. It is concluded that these changes in flow-volume curve configuration reflect a decrease in inhomogeneously distributed inflammatory airway narrowing.
Related Concept Videos
05:18Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
06:16Rat Heterotopic Abdominal Heart/Single-lung Transplantation in a Volume-loaded Configuration
09:49Measurement of the Pressure-volume Curve in Mouse Lungs
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
Maximum Power Flow and Line Loadability
Electron Configuration of Multielectron Atoms
