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[Effect of transcranial electrical stimulation on sleep in rats]
I Lendais1, F Chaouloff, D Laude
1Laboratoire d'Electrophysiologie, Faculté de Chirurgie dentaire, Montrouge.
Abstract:
Transcranial electrical stimulation with high frequency intermittent current (Limoge's current) was delivered to normal rats and to PCPA-treated rats with impaired sleep. Electrocorticogram was continuously recorded for quantifying the stage of the sleep-waking cycle. The current did not affect the sleep pattern of normal rats whereas the number of paradoxical sleep episodes increased in insomniac animals. The increased duration of paradoxical sleep in PCPA-treated rats favored the recovery of sleep in this group. The stimulation increased the brain serotonin turnover, which could possibly contribute to its hypnogenic action.