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Updated: Aug 16, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
Abstract:
The total plasma protein S levels in 35 normal persons and 26 pregnant women were examined, using the immunoelectrophoresis method. The results showed a considerably lower level of total plasma protein S in the pregnant women than in the non-pregnant (94.9 +/- 18.4%/107.8 +/- 16.9%, P less than 0.05), but no significant difference existed between the normal men and women (P greater than 0.05). Moreover, a significant decrease was observed in the free plasma protein S with cofactor activity, in the pregnant women. This decline may be involved in the acceleration of the hypercoagulative state and the risk of thrombosis in the pregnant women.
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