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Metabolic syndrome in IgA glomerulonephritis
Kati Kaartinen1, Jaana Syrjänen2, Ilkka Pörsti2
1School of Medicine, University of Tampere, Savonlinna, Finland.
Nephron Extra
|October 23, 2014
Summary
Metabolic syndrome (MetS) prevalence in IgA glomerulonephritis (IgAGN) patients mirrors the general population. While univariate analysis suggested a link, MetS was not an independent predictor of IgAGN progression.
Area of Science:
- Nephrology
- Endocrinology
- Epidemiology
Background:
- Metabolic syndrome (MetS) is a potential risk factor for chronic kidney disease.
- IgA glomerulonephritis (IgAGN) is a common primary glomerulopathy.
Purpose of the Study:
- To determine the prevalence of MetS in IgAGN patients.
- To investigate the impact of MetS on IgAGN disease progression.
Main Methods:
- Retrospective study of 174 IgAGN patients.
- Assessment of MetS using Alberti et al. criteria over 11-16 years.
- Utilized various glomerular filtration markers.
Main Results:
- MetS prevalence was 39% at the first visit, similar to the general Finnish population.
- Univariate analysis showed MetS associated with IgAGN progression.
- Multivariate analysis indicated MetS is not an independent prognostic determinant.
Conclusions:
- MetS prevalence is comparable between IgAGN patients and the general population in Finland.
- MetS is not an independent prognostic factor for IgAGN progression.
Keywords:
CreatinineCystatin-CEstimated glomerular filtration rateIgA glomerulonephritisMetabolic syndromeMore Related Videos
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