Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

736
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
736
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

480
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
480
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

729
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
729
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

512
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
512
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

466
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
466
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

2.5K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of performance and utility of mortality prediction models in a single Indian mixed tertiary intensive care unit.

International journal of critical illness and injury science·2014
Same author

India's twin epidemic: Prevalence data from a single mixed tertiary intensive care unit.

Indian journal of endocrinology and metabolism·2013
Same journal

Circulating metabolome as key biomarkers for ventilator-associated pneumonia: Case-Control study in a tertiary care hospital of North India.

International journal of critical illness and injury science·2026
Same journal

Toward an "accordion intensive care unit" model: A flexible, patient-centered approach to critical-care capacity.

International journal of critical illness and injury science·2026
Same journal

Evaluating the diagnostic utility of heart-type fatty acid-binding protein as a novel biomarker for acute coronary syndrome in the emergency department: A 1-year cross-sectional study.

International journal of critical illness and injury science·2026
Same journal

Prognostic accuracy of mid-regional proadrenomedullin in patients with sepsis - A longitudinal observational study.

International journal of critical illness and injury science·2026
Same journal

Back to basics in critical care: Can hematological ratios refine sepsis risk stratification?

International journal of critical illness and injury science·2026
Same journal

Evaluating the role of high-dose intravenous thiamine supplementation for lactate clearance in patients with cirrhosis and sepsis.

International journal of critical illness and injury science·2026
See all related articles

Related Experiment Video

Updated: Apr 21, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
13:08

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

19.9K

D Dimer in acute care.

Prachee M Sathe1, Urvil D Patwa1

  • 1Department of Critical Care Medicine, Ruby Hall Clinic, Pune, Maharashtra, India.

International Journal of Critical Illness and Injury Science
|October 23, 2014
PubMed
Summary
This summary is machine-generated.

D-dimer testing is common in intensive care units but often misinterpreted. Understanding D-dimer levels and their significance is crucial for accurate diagnosis and prognosis in conditions like pulmonary embolism and deep vein thrombosis.

Keywords:
D-DimerDeep vein thrombosisDisseminated intravascular coagulationpulmonary embolism

More Related Videos

The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit
08:22

The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit

Published on: December 12, 2025

1.5K
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.1K

Related Experiment Videos

Last Updated: Apr 21, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
13:08

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

19.9K
The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit
08:22

The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit

Published on: December 12, 2025

1.5K
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.1K

Area of Science:

  • Critical Care Medicine
  • Hematology
  • Diagnostic Testing

Background:

  • Pulmonary embolism, Deep Vein Thrombosis (DVT), and Disseminated Intravascular Coagulation (DIC) are significant causes of mortality and morbidity in the Intensive Care Unit (ICU).
  • D-dimer is frequently utilized as an investigation in these critical conditions.
  • Misinterpretation of D-dimer results can lead to diagnostic errors.

Purpose of the Study:

  • To clarify the role and interpretation of D-dimer testing in critical care settings.
  • To review conditions associated with elevated D-dimer levels.
  • To explore the prognostic value of D-dimer in specific conditions such as intracranial hemorrhage and gastrointestinal bleeding.

Main Methods:

  • Literature review focusing on D-dimer testing.
  • Analysis of D-dimer's significance in various clinical conditions.
  • Evaluation of D-dimer's prognostic implications.

Main Results:

  • D-dimer is a sensitive but not specific marker.
  • Elevated D-dimer levels are associated with thrombotic events and other conditions.
  • D-dimer may offer prognostic insights in intracranial hemorrhage and GI bleeds.

Conclusions:

  • Accurate interpretation of D-dimer is essential to avoid diagnostic pitfalls in ICU patients.
  • Understanding the limitations and applications of D-dimer testing improves patient management.
  • Further research into D-dimer's prognostic role is warranted.