The histologic and electronmicroscopic study of melanoblastoma after argon-laser therapy

The left eye was enucleated for secondary detachment in a 50-year-old patient, with choroid melanoblastoma treated with argon-laser photocoagulation six months before. Histological examination of the enucleated eyeball showed pigmented melanoblastoma with some focal fibrosis in the area of the previous laser treatment. There were no signs of an actual tumour cell damage on electron microscopy. The fibrosis found at the side of laser treatment was very likely to result from the local therapeutical tumour destruction which, however, was not sufficient to influence substantially its further growth.