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A quartz crystal microbalance method to study the terminal functionalization of glycosaminoglycans

Dhruv Thakar1, Elisa Migliorini, Liliane Coche-Guerente

  • 1Université Grenoble Alpes, DCM, 38000 Grenoble, France.

Chemical Communications (Cambridge, England)
|October 24, 2014
PubMed

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Glycosaminoglycans

Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
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