Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Processed foods in the context of a vegan diet, and changes in body weight and severe hot flashes in postmenopausal women: a secondary analysis of a randomized clinical trial.

Menopause (New York, N.Y.)·2026

Same author

Plant protein and body weight in postmenopausal women: a secondary analysis from a randomized clinical trial.

Menopause (New York, N.Y.)·2026

Same author

Environmental Footprint of a Low-Fat Vegan Diet in People With Type 1 Diabetes: A Secondary Analysis of a Randomized Clinical Trial.

Current developments in nutrition·2026

Same author

When Nutrition Science Is Ignored: Potential Public Health Cost of the 2025 Dietary Guidelines.

JAMA·2026

Same author

Plant-based dietary index on the Mediterranean and a vegan diet: a secondary analysis of a randomized, cross-over trial.

Frontiers in nutrition·2025

Same author

Vegan Diet, Greenhouse Gas Emissions, and Cumulative Energy Demand: A Secondary Analysis of a Randomized Clinical Trial.

JAMA network open·2025

Search research articles

Related Experiment Video

Updated: Apr 21, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Nutrition intervention for migraine: a randomized crossover trial.

Anne E Bunner¹, Ulka Agarwal, Joseph F Gonzales

¹Physicians Committee for Responsible Medicine, 5100 Wisconsin Ave, NW, Suite 400, Washington, DC 20016, USA. abunner@pcrm.org.

The Journal of Headache and Pain

|October 24, 2014

Summary

A low-fat plant-based diet significantly reduced migraine pain severity in a 36-week study. While diet improved pain, further research is needed to confirm its role in migraine management.

More Related Videos

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

Related Experiment Videos

Last Updated: Apr 21, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research

Published on: January 5, 2024

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

Area of Science:

Neurology
Nutrition Science
Clinical Research

Background:

Migraine treatment lacks definitive dietary guidelines.
Dietary interventions show potential for migraine management.
Evidence for specific dietary impacts on migraine is limited.

Purpose of the Study:

To evaluate the efficacy of a low-fat plant-based diet intervention on migraine severity and frequency.
To compare a dietary intervention against a placebo supplement in migraine sufferers.

Main Methods:

A 36-week crossover study involving 42 adult migraine sufferers.
Participants underwent a 16-week low-fat vegan and elimination diet period, followed by a placebo supplement period, with a 4-week washout.
Assessments included visual analog scale for pain, headache intensity, and frequency, analyzed using student's t-tests.

Main Results:

The low-fat vegan diet significantly reduced worst headache pain (p=0.03) and showed greater overall pain improvement (p<0.001) compared to placebo.
Average headache intensity and frequency showed non-significant declines during the diet period.
Patient's Global Impression of Change indicated greater pain improvement with the dietary intervention.

Conclusions:

A nutritional approach, specifically a low-fat plant-based diet, may be beneficial for migraine treatment.
The study highlights the potential of dietary changes in managing migraine symptoms.
Methodological considerations warrant further investigation into dietary interventions for migraine.