Related Experiment Video
Updated: Apr 21, 2026

08:04
Design of a Biaxial Mechanical Loading Bioreactor for Tissue Engineering
Published on: April 25, 2013
13.9K
A tensile machine with a novel optical load cell for soft biological tissues application
Rahim Faturechi1, Ata Hashemi, Nabiollah Abolfathi
1Biomedical Engineering Department, Amirkabir University of Technology , Tehran , Iran.
Journal of Medical Engineering & Technology
|October 24, 2014
Summary
Researchers developed a low-cost uniaxial tensile testing machine for soft biological tissues. This novel device uses an optical digital microscope and a beam-based load cell, offering accurate mechanical property measurements for research centers.
Area of Science:
- Biomaterials Engineering
- Mechanical Engineering
- Tissue Mechanics
Background:
- Uniaxial tensile testing machines are crucial for material mechanical property assessment.
- Existing devices are often costly, limiting access for smaller research facilities.
- There is a need for affordable, high-precision testing equipment for soft biological tissues.
Purpose of the Study:
- To design and fabricate a novel, low-cost uniaxial tensile testing machine.
- To enable accurate measurement of mechanical properties in soft biological tissues.
- To provide a cost-effective solution for small research centers.
Main Methods:
- A new low-cost beam-based load cell was designed, with stiffness determined theoretically and experimentally (100 N/mm).
- Optical deflection measurement of the load cell was achieved using a digital microscope with 1 µm accuracy.
- An in-house image processing program analyzed the force-time behavior of tissue specimens.
Main Results:
- The fabricated uniaxial tensile testing machine accurately measured soft tissue mechanical properties.
- Measurements of amnion tissue demonstrated strong agreement with previously published data.
- The load cell's stiffness was adjustable, accommodating various tissue strengths.
Conclusions:
- The developed low-cost uniaxial tensile testing machine is effective for soft biological tissue analysis.
- This innovation enhances accessibility to advanced mechanical testing for smaller research institutions.
- The device offers a reliable and affordable method for characterizing tissue biomechanics.

