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Updated: Apr 21, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

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Human herpes simplex virus type 1 in confiscated gorilla.

Kirsten V K Gilardi, Kristie L Oxford, David Gardner-Roberts

Emerging Infectious Diseases

|October 24, 2014

Summary

Human herpes simplex virus type 1 was found in a juvenile gorilla in 2007, causing stomatitis. This case highlights the risk of pathogen transmission between humans and nonhuman primates.

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Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

Area of Science:

Veterinary Medicine
Primate Health
Infectious Diseases

Background:

Understanding zoonotic disease transmission is crucial for conservation efforts.
Gorillas are susceptible to various pathogens, including those shared with humans.

Observation:

A juvenile eastern lowland gorilla (Gorilla beringei graueri) presented with stomatitis in 2007.
The affected gorilla had significant direct contact with human caretakers.

Findings:

Human herpes simplex virus type 1 (HSV-1) was detected in the gorilla.
The virus caused severe stomatitis in the nonhuman primate.

Implications:

This case confirms the potential for pathogen transfer from humans to nonhuman primates.
It underscores the importance of stringent biosecurity measures in facilities housing endangered species.
Further research into interspecies disease transmission is warranted to protect both human and animal populations.