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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Diabetic Nephropathy01:28

Diabetic Nephropathy

4
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration...
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Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

5
Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Predictions of ocular changes caused by diabetes in glaucoma patients.

Computer methods and programs in biomedicine·2017
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INFLUENCE OF GLAUCOMA ON DIABETES-INDUCED CHANGES IN THE ANTERIOR OCULAR SEGMENT.

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2016
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SHORT TERM EVALUATION OF PERIMETRIC PROGRESSION IN PATIENTS WITH OPEN ANGLE GLAUCOMA AND DIABETES.

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2016
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INTRAOCULAR BIODISTRIBUTION OF INTRAVITREAL INJECTED FLUORESCENT DEXAMETHASONE-CHITOSAN NANOPARTICLES IN RABBIT EYES.

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Glaucoma evolution in patients with diabetes.

Nicoleta Anton Apreutesei, D Chiselita, O I Motas

    Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
    |October 25, 2014
    PubMed
    Summary

    This study investigated glaucoma screening in diabetic patients, finding no significant differences in intraocular pressure or visual field progression between those with and without diabetic retinopathy. Further research is needed to understand this relationship.

    Area of Science:

    • Ophthalmology
    • Endocrinology
    • Chronic disease management

    Background:

    • Glaucoma and diabetes mellitus (DM) are chronic conditions with a suspected link.
    • Diabetic retinopathy is a known complication of DM that can affect vision.

    Purpose of the Study:

    • To screen for glaucoma in patients diagnosed with diabetes mellitus.
    • To analyze the relationship between glaucoma and diabetic retinopathy in a patient cohort.

    Main Methods:

    • Retrospective study of 92 eyes from 46 patients with primitive open angle glaucoma (POAG) and intraocular hypertension (OHT).
    • Patients with diabetes mellitus (DM) were categorized into two groups: with diabetic retinopathy (group 1) and without (group 2).
    • Analyzed parameters included intraocular pressure (IOP), visual field progression (computerized perimetry), and fundus condition (diabetic retinopathy).

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    Main Results:

    • Patients with glaucoma and diabetic retinopathy showed a mean IOP difference of 4.95 mmHg and a mean visual field (MD) depreciation of 4.18 dB.
    • Patients with glaucoma but without diabetic retinopathy had a mean IOP difference of 1.63 mmHg and MD depreciation of 0.65 dB.
    • Mild changes were predominant in proliferative diabetic retinopathy; non-proliferating diabetic retinopathy had a marginal statistical influence on glaucoma progression.

    Conclusions:

    • No statistically significant differences in intraocular pressure or visual field changes were observed between the groups.
    • Non-proliferating diabetic retinopathy showed a marginal statistical influence on the progression of glaucoma.
    • Further large-scale prospective studies are recommended for long-term follow-up and definitive conclusions.