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Predictors of coronary artery disease in patients with Behçet's disease

Ambarish Pandey1, Jalaj Garg, Parasuram Krishnamoorthy

  • 1Division of Cardiology, Department of Medicine, University of Texas, Dallas, Tex., USA.

Cardiology
|October 25, 2014
PubMed

Insights

Behçet

Area of Science:

  • Cardiovascular Medicine
  • Rheumatology
  • Epidemiology

Background:

  • Behçet's disease (BD) is a rare multisystem vasculitis with unknown causes.
  • Coronary artery disease (CAD) is a serious complication that can affect patients with BD.

Purpose of the Study:

  • To determine the prevalence of coronary artery disease (CAD) in patients with Behçet's disease (BD).
  • To identify predictors of CAD in individuals diagnosed with BD.

Main Methods:

  • Utilized the National Inpatient Sample database (2009-2010) for adult patients diagnosed with BD (ICD-9 code 136.1).
  • Analyzed demographic data, traditional cardiovascular risk factors, and CAD prevalence using ICD-9 codes.
  • Employed multimodel regression analysis to identify independent predictors of CAD.

Main Results:

  • The prevalence of BD was 0.006% among US in-hospital admissions.
  • The prevalence of CAD in BD patients was 12.1%.
  • Hypertension (OR=2.20) and hyperlipidemia (OR=2.34) were significant independent predictors of CAD in this cohort.

Conclusions:

  • Traditional cardiovascular risk factors in BD patients resemble those in the general population.
  • The findings suggest an accelerated atherosclerosis process in BD patients, evidenced by the young age of those with CAD.
Abstract

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