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Complete Genome Sequence of Type Strain Pasteurella multocida subsp. multocida ATCC 43137

K W Davenport1, H E Daligault1, T D Minogue2

  • 1Los Alamos National Laboratory (LANL), Los Alamos, New Mexico, USA.

Genome Announcements
|October 25, 2014
PubMed

Insights

Pasteurella multocida causes aggressive soft-tissue infections in humans, often from pet injuries. Researchers sequenced the P. multocida type strain genome, providing a resource for studying these infections.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Soft-tissue infections caused by Pasteurella multocida are frequently linked to domestic animal bites or scratches.
  • These Pasteurella multocida infections can progress rapidly and become severe in humans.

Purpose of the Study:

  • To make the genome sequence of the Pasteurella multocida type strain publicly available.
  • To provide a genomic resource for understanding Pasteurella multocida pathogenesis and developing treatments.

Main Methods:

  • Whole-genome sequencing of the Pasteurella multocida subsp. multocida ATCC 43137 type strain.
  • Bioinformatic analysis and assembly of the resulting sequence data.

Main Results:

  • The complete genome of P. multocida ATCC 43137 was assembled into a single closed chromosome.
  • The chromosome size is 2,271,840 base pairs with a G+C content of 40.4%.

Conclusions:

  • The availability of the P. multocida ATCC 43137 genome sequence facilitates further research into its biology and role in human infections.
  • This genomic data serves as a foundation for comparative genomics and the identification of virulence factors.

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