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Complete Genome Sequence of Type Strain Pasteurella multocida subsp. multocida ATCC 43137.
K W Davenport1, H E Daligault1, T D Minogue2
1Los Alamos National Laboratory (LANL), Los Alamos, New Mexico, USA.
Genome Announcements
|October 25, 2014
Summary
Pasteurella multocida causes aggressive soft-tissue infections in humans, often from pet injuries. Researchers sequenced the P. multocida type strain genome, providing a resource for studying these infections.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Soft-tissue infections caused by Pasteurella multocida are frequently linked to domestic animal bites or scratches.
- These Pasteurella multocida infections can progress rapidly and become severe in humans.
Purpose of the Study:
- To make the genome sequence of the Pasteurella multocida type strain publicly available.
- To provide a genomic resource for understanding Pasteurella multocida pathogenesis and developing treatments.
Main Methods:
- Whole-genome sequencing of the Pasteurella multocida subsp. multocida ATCC 43137 type strain.
- Bioinformatic analysis and assembly of the resulting sequence data.
Main Results:
- The complete genome of P. multocida ATCC 43137 was assembled into a single closed chromosome.
- The chromosome size is 2,271,840 base pairs with a G+C content of 40.4%.
Conclusions:
- The availability of the P. multocida ATCC 43137 genome sequence facilitates further research into its biology and role in human infections.
- This genomic data serves as a foundation for comparative genomics and the identification of virulence factors.
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