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Diabetic nephropathy - complications and treatment
1Department of Nephrology, Monash Medical Center, Monash Health, Clayton, VIC, Australia ; Department of General Medicine, Dandenong Hospital, Monash Health, Clayton, VIC, Australia ; Department of Medicine, Monash University, Clayton, VIC, Australia.
International Journal of Nephrology and Renovascular Disease
|October 25, 2014
Summary
Diabetic nephropathy, a leading cause of kidney failure, is increasingly understood through basic science. This review explores current management and novel treatments for diabetic kidney disease.
Area of Science:
- Nephrology
- Endocrinology
- Pathophysiology
Background:
- Diabetic nephropathy is a major global cause of chronic kidney disease (CKD) and end-stage renal failure.
- Extensive research has improved understanding of its pathophysiology and therapeutic options.
Purpose of the Study:
- To review current diabetic nephropathy management strategies.
- To examine basic science and pathophysiology relevant to novel investigative treatments.
Main Methods:
- Literature review of basic science research.
- Analysis of clinical therapeutics and pathophysiology.
- Examination of novel and investigative treatment strategies.
Main Results:
- Enhanced understanding of diabetic nephropathy pathophysiology.
- Expanded potential therapies for diabetic kidney disease.
- Integration of basic science with clinical management approaches.
Conclusions:
- Current management of diabetic nephropathy benefits from understanding its underlying pathophysiology.
- Investigative strategies offer promising new avenues for treating diabetic kidney disease.
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