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Updated: Apr 21, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Dry age-related macular degeneration: A currently unmet clinical need
Jean-François Girmens1, José-Alain Sahel2, Katia Marazova3
1French National Institute of Health and Medical Research, Paris, France; ; Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris, France;
Abstract:
Age-related macular degeneration (AMD) is a leading cause of severe visual impairment and disability in older people worldwide. Although considerable advances in the management of the neovascular form of AMD have been made in the last decade, no therapy is yet available for the advanced dry form of AMD (geographic atrophy). This review focuses on current trends in the development of new therapies targeting specific pathophysiological pathways of dry AMD. Increased understanding of the complex mechanisms that underlie dry AMD will help to address this largely unmet clinical need.
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