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Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex
G C Miescher1, M Schreyer, H R MacDonald
1Ludwig Institute for Cancer Research, Lausanne Branch, Epalinges, Switzerland.
Immunology Letters
|December 1, 1989
We describe the production of a rat monoclonal antibody, 17A2, that detects the T cell receptor-associated CD3 molecular complex. 17A2 cross-competes with a CD3 epsilon-specific reagent and similarly stimulates IL-2 production by T cells. Immunohistological and cell separation applications are shown.
We describe the production of a rat monoclonal antibody, 17A2, that detects the T cell receptor-associated CD3 molecular complex. 17A2 cross-competes with a CD3 epsilon-specific reagent and similarly stimulates IL-2 production by T cells. Immunohistological and cell separation applications are shown.