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Related Concept Videos

Obesity01:24

Obesity

1.5K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.5K
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

353
In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
353
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

430
Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
430
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

317
Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
317
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

622
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
622

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Updated: Apr 21, 2026

Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion
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Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion

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Obesity, orthopaedics, and outcomes.

William M Mihalko, Patrick F Bergin, Frank B Kelly

    The Journal of the American Academy of Orthopaedic Surgeons
    |October 26, 2014
    PubMed
    Summary

    Obesity is common in orthopedic patients and linked to other health issues. Despite risks, orthopedic surgery can significantly relieve pain and enhance quality of life for obese individuals.

    Area of Science:

    • Orthopaedic surgery
    • Public health

    Background:

    • Obesity is a prevalent health condition affecting a growing number of patients undergoing orthopedic procedures.
    • Obesity is frequently comorbid with conditions such as diabetes, cardiovascular disease, pulmonary disease, metabolic syndrome, and obstructive sleep apnea.
    • These comorbidities necessitate specialized preoperative and postoperative management strategies to optimize patient outcomes.

    Purpose of the Study:

    • To highlight the challenges and benefits of orthopedic procedures in obese patients.
    • To emphasize the need for tailored perioperative care in this population.

    Main Methods:

    • Review of existing literature on obesity in orthopedic surgery.
    • Analysis of perioperative risks and benefits associated with orthopedic interventions in obese individuals.

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    Main Results:

    • Obese patients face increased risks of perioperative complications.
    • Orthopedic procedures can still provide substantial pain relief and improve quality of life for obese patients.
    • Management of comorbidities is crucial for successful surgical outcomes.

    Conclusions:

    • Despite potential complications, orthopedic surgery remains a viable option for pain management and functional improvement in obese patients.
    • Careful preoperative and postoperative planning is essential to mitigate risks and maximize benefits for this patient group.