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Updated: Apr 21, 2026
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Daptomycin and methicillin-resistant Staphylococcus aureus isolated from a catheter-related bloodstream infection: a
Fernanda S Cavalcante, Dennis de C Ferreira, Raiane C Chamon
1Departamento de Microbiologia Médica, Laboratório de Infecção Hospitalar/UFRJ, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Av, Carlos Chagas Filho, 373, CEP: 21941-590, Rio de Janeiro, Brazil. santoskrn@micro.ufrj.br.
Background:
Daptomycin is an alternative option for the treatment of catheter-related bloodstream-infections caused by methicillin-resistant Staphylococcus aureus. This study reports a case of a daptomycin and methicillin-resistant Staphylococcus aureus isolate recovered from the blood of a Brazilian patient undergoing hemodialysis.
Case Presentation:
A 64-year-old white male patient suffering from diabetes mellitus, systolic hypertension, heart disease with a coronary stent, obesity and chronic renal failure and on use of permcath catheter developed a catheter-related bloodstream-infection by a daptomycin-methicillin-resistant Staphylococcus aureus isolate after one month of daptomycin therapy. The isolate was identified as the SCCmec II/USA100/sequence type 5 lineage by molecular techniques.
Conclusions:
In this work we described a Brazilian patient with bloodstream infection caused by a daptomycin and methicillin-resistant Staphylococcus aureus belonging to the lineage USA100/sequence type 5. Our case highlights the careful management of bloodstream infections and the importance of the judicious use of antimicrobials due the possibility of daptomycin-resistance developing among S. aureus isolates, especially in patients under hemodialysis, which are frequently exposed to vancomycin and daptomycin therapy.
