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Reduction of bladder activity on FDG PET/CT scan in patients with urinary bladder carcinoma. A prospective study with
1Wan-Yu Lin, MD, Department of Nuclear Medicine, Taichung Veterans General Hospital, 1650, Taiwan Boulevard, Sec. 4, Taichung 407, Taiwan, Tel. (886)4/23 74 13 49, Fax (886)4/23 74 13 48,
Unlabelled:
Oral hydration with large volume of fluid, high dose of diuretics and maximum bladder distension are frequently required to achieve an adequate urinary FDG clearance in an FDG PET/CT protocol for bladder cancer or pelvic tumour evaluation. Although most patients tolerated these procedures for eliminating urinary FDG activity, these procedures may be still unpleasant.
Aim:
Is there a more patient-friendly protocol which is less burdensome and yet provides a satisfactory FDG clearance in urine? In this study, we established a patient-friendly FDG PET/CT protocol without compromising urinary FDG clearance.
Patients, Methods:
23 patients with biopsy-proven urinary bladder cancers were recruited to evaluate the effectiveness of this patient-friendly protocol on reducing urinary bladder FDG activity. The patient-friendly protocol includes encouraging patients to take a tolerable amount of fluid, delaying the administration of low dose diuretic, shortening the urine holding time and using delayed imaging.
Results:
All of the patients tolerated this patient-friendly procedure well. In addition, the patient-friendly protocol was effective in reducing FDG activity in the urine. One hundred percent of primary bladder cancer were visualized on the FDG PET/CT images using this patient-friendly protocol.
Conclusions:
This patient-friendly FDG PET/CT protocol is less intrusive yet effective in reducing urinary FDG activity.
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