Related Experiment Video
Updated: Apr 21, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
Generic Feature Selection with Short Fat Data
1Department of Statistics, University of Nebraska-Lincoln, Lincoln, NE, 68583, USA.
Abstract:
Consider a regression problem in which there are many more explanatory variables than data points, i.e., p ≫ n. Essentially, without reducing the number of variables inference is impossible. So, we group the p explanatory variables into blocks by clustering, evaluate statistics on the blocks and then regress the response on these statistics under a penalized error criterion to obtain estimates of the regression coefficients. We examine the performance of this approach for a variety of choices of n, p, classes of statistics, clustering algorithms, penalty terms, and data types. When n is not large, the discrimination over number of statistics is weak, but computations suggest regressing on approximately [n/K] statistics where K is the number of blocks formed by a clustering algorithm. Small deviations from this are observed when the blocks of variables are of very different sizes. Larger deviations are observed when the penalty term is an L norm with high enough q.
Related Concept Videos
Survival Tree
Building a Survival Tree
Constructing a...
Sample Size Calculation
The sample size for the given experiment or sampling effort is fundamental to any study design. Sample size decides the number of...
One-Way ANOVA: Unequal Sample Sizes
Cluster Sampling Method
To choose a cluster sample, divide the population into clusters (groups) and then randomly select some of the clusters. All the members from these clusters are in the cluster sample. For example, if you randomly sample four departments from your...
One-Way ANOVA: Equal Sample Sizes
Different sample means can result in different values for the variance estimate: variance between samples. This is because the variance between samples is calculated as the product of the sample size and the variance between the...
Sampling Plans
Random sampling is a method where each member of the population has an equal chance of being selected for the sample. It involves selecting individuals randomly, often using random number generators or lottery-type methods. For example, when analyzing the properties of a...

