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BK channel activators and their therapeutic perspectives

Bo H Bentzen1, Søren-Peter Olesen2, Lars C B Rønn3

  • 1Department of Biomedical Sciences, Faculty of Health Sciences, Danish Arrhythmia Research Centre, University of Copenhagen Copenhagen, Denmark ; Acesion Pharma Copenhagen, Denmark.

Frontiers in Physiology
|October 28, 2014
PubMed
Summary

The large conductance calcium- and voltage-activated K(+) channel (BK channel) integrates cellular signals to regulate physiological functions. Small organic molecules activating BK channels are crucial tools for understanding its roles in health and disease.

Keywords:
BKKCNMA1KCa1.1MaxiKactivatorshigh-conductance calcium-activated potassium channelsopenerspharmacology

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