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The treatment of Graves' disease in children and adolescents
Hae Sang Lee1, Jin Soon Hwang1
1Department of Pediatrics, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea.
Abstract:
Graves' disease (GD) accounts for 10%-15% of thyroid disorders in children and adolescents. The use of antithyroid drugs as the initial treatment option in GD is well accepted. An average two years remission is achieved in about 30% of children treated with antithyroid drugs. However, the optimal treatment duration and the predictive marker of remission after antithyroid drug therapy are still controversial. Additionally, (131)I therapy and surgery are considered the option for treatment in children and adolescents with GD. We review the treatment options for pediatric GD and the possible determinants of remission and relapse on antithyroid drug treatment in children and adolescents.
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