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Circulating fetuin-A in patients with pancreatic cancer: a hospital-based case-control study
Maria Dalamaga1, Stergios A Polyzos, Konstantinos Karmaniolas
1Department of Clinical Biochemistry, Medical School, University of Athens, "Attikon" General University Hospital , Athens , Greece .
Context:
A proteomic analysis has proposed fetuin-A (alpha-2-HS-glycoprotein) as a new potential marker for pancreatic cancer (PC).
Objective:
Circulating fetuin-A levels in patients with PC.
Methods:
Serum fetuin-A was measured in 81 cases with PC and 81 matched controls before the initiation of any treatment.
Results:
Serum fetuin-A was not independently associated with the presence of PC. Although there was a trend with higher fetuin-A levels across PC stages, comparisons of fetuin-A in patients within different PC prognostic stages revealed no differences.
Conclusions:
Circulating fetuin-A was similar between patients and controls and was not associated with the disease severity.
