Spatial dynamics for a model of epidermal wound healing
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Updated: Apr 21, 2026

Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding
Published on: February 26, 2015
1Division of Mathematical and Natural Sciences, Arizona State University, Phoenix, AZ 85069-7100, United States. Haiyan.Wang@asu.edu.
Abstract:
In this paper, we consider the spatial dynamics for a non-cooperative diffusion system arising from epidermal wound healing. We shall establish the spreading speed and existence of traveling waves and characterize the spreading speed as the slowest speed of a family of non-constant traveling wave solutions. We also construct some new types of entire solutions which are different from the traveling wave solutions and spatial variable independent solutions. The traveling wave solutions provide the healing speed and describe how wound healing process spreads from one side of the wound. The entire solution exhibits the interaction of several waves originated from different locations of the wound. To the best of knowledge of the authors, it is the first time that it is shown that there is an entire solution in the model for epidermal wound healing.
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