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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
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Related Experiment Video

Updated: Apr 21, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Published on: April 27, 2014

A new paradigm in chronic bladder pain.

Ursula Wesselmann

Journal of Pain & Palliative Care Pharmacotherapy

|October 29, 2014

Summary

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a complex condition often underdiagnosed. Management requires a multidisciplinary approach, integrating physical, psychosocial, and sexual health for comprehensive patient care.

Area of Science:

Urology
Pain Medicine
Psychosomatic Medicine

Background:

Visceral pain conceptualization has evolved from organ-specific disease to mechanism-based understanding.
Interstitial cystitis/bladder pain syndrome (IC/BPS) encompasses all patients experiencing bladder pain.
IC/BPS shares significant overlap with other pelvic and abdominal pain syndromes.

Purpose of the Study:

To highlight the evolving understanding of visceral pain.
To emphasize the broad scope of IC/BPS.
To advocate for improved diagnosis and management of IC/BPS.

Main Methods:

Review of current concepts in visceral pain.
Discussion of the diagnostic criteria and scope of IC/BPS.
Analysis of the overlap with other pain syndromes.

Keywords:

bladder interstitial cystitis multidisciplinary approach pain visceral

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Last Updated: Apr 21, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

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Main Results:

IC/BPS is likely underdiagnosed and undertreated in both men and women.
A multidisciplinary team approach is essential for effective IC/BPS management.
Integrating psychosocial and sexual dimensions is crucial for understanding visceral pain.

Conclusions:

The conceptualization of visceral pain now includes pathophysiological mechanisms and psychosocial factors.
IC/BPS represents a significant clinical challenge due to underdiagnosis and undertreatment.
Effective management of IC/BPS necessitates a comprehensive, multidisciplinary strategy.