Related Experiment Video
Updated: Apr 21, 2026

Picometer-Precision Atomic Position Tracking through Electron Microscopy
Published on: July 3, 2021
Less is more: how compressed sensing is transforming metrology in chemistry
Daniel J Holland1, Lynn F Gladden
1Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 3RA (UK). djh79@cam.ac.uk.
Abstract:
Mathematics has had a profound impact on science, providing a means to understand the world around us in unprecedented ways. With the advent of the digital age, the subject of information theory has grown hugely in importance. In particular, over the last two decades significant advances in our understanding of sampling and function reconstruction have culminated in the development of an idea known as compressed sensing. What seems like an abstract idea is now having a profound impact throughout the scientific world-from enabling high-resolution imaging of pediatric patients in clinical medicine through to advancing 3D electron tomography images of nanoparticle catalysts and NMR spectroscopy studies of proteins. In this Minireview, we summarize these applications and provide an outlook on how the principles of compressed sensing are leading to entirely new approaches to measurement throughout the physical and life sciences.
Related Concept Videos
SI Units: 2019 Redefinition
A standard set of units has been defined...
Measurement: Derived Units
Mass Analyzers: Overview
Coulometry: Overview
Instrument Calibration
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
Measurement: Standard Units

