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During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
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Related Experiment Video

Updated: Apr 21, 2026

Isolation of Endothelial Progenitor Cells from Healthy Volunteers and Their Migratory Potential Influenced by Serum Samples After Cardiac Surgery
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Endothelial dysfunction after non-cardiac surgery: a systematic review.

E S Søndergaard1, S Fonnes, I Gögenur

  • 1Department of Anesthesiology, Roskilde Hospital, Roskilde, Denmark.

Acta Anaesthesiologica Scandinavica
|October 29, 2014
PubMed
Summary

Non-cardiac surgery can impair endothelial function, as indicated by non-invasive markers. Assessing endothelial function pre- and post-operatively may help prevent post-operative myocardial damage.

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Area of Science:

  • Cardiovascular research
  • Surgical outcomes
  • Vascular biology

Background:

  • Over 50% of patients with elevated troponin post-non-cardiac surgery exhibit pre-operative endothelial dysfunction.
  • Non-invasive markers for endothelial function assessment have been developed.
  • Endothelial dysfunction is a significant concern in post-operative cardiac events.

Purpose of the Study:

  • To systematically review literature evaluating the association between non-cardiac surgery and non-invasive markers of endothelial function.
  • To understand the impact of surgery on endothelial health.

Main Methods:

  • Systematic literature search conducted in MEDLINE, EMBASE, and Cochrane Library.
  • Inclusion of studies measuring endothelial function non-invasively, both pre- and post-operatively.
  • Analysis of all non-cardiac surgery types across all age groups and genders.

Main Results:

  • Five studies met the inclusion criteria from 1722 initially identified.
  • Endothelial function was found to be disturbed in patients following non-cardiac surgery.
  • Three studies reported a significant decrease in endothelial function 2-24 hours post-surgery.
  • Two studies indicated improvement in endothelial function one month after surgery in specific patient groups (renal transplantation, vascular surgery).

Conclusions:

  • Endothelial function demonstrably changes in relation to surgical procedures.
  • Non-invasive assessment of endothelial function holds potential for guiding clinical strategies.
  • This assessment can aid in preventing or treating post-operative myocardial damage.