Laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease in infants

Ling Leung1, Carol Wing Yan Wong, Patrick Ho Yu Chung

  • 1Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong.

Insights

Laparoscopic Nissen fundoplication is safe and effective for infants with gastro-oesophageal reflux disease (GERD), showing outcomes comparable to older children. This procedure offers a shorter operative duration and low recurrence rates for infant GERD management.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology

Background:

  • Limited data exists on laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease (GERD) in infants.
  • This study describes the experience with this procedure in children, focusing on infants under 12 months.

Purpose of the Study:

  • To evaluate the safety and efficacy of laparoscopic Nissen fundoplication in infants compared to older children.
  • To assess surgical outcomes, including operative time, complications, and recurrence rates.

Main Methods:

  • Retrospective review of paediatric patients who underwent laparoscopic fundoplication for GERD between 1998 and 2013.
  • Patients were divided into two groups: infants (0-12 months) and older children (>12 months).
  • Data collected included indications, demographics, operative time, blood loss, conversions, complications, recurrences, and hospitalization duration.

Main Results:

  • 86 patients were reviewed (21 infants, 65 older children).
  • Operative time was shorter in infants (157 min vs. 169 min).
  • Surgical outcomes were comparable between groups, with low recurrence (0% vs. 3%) and complication rates (9.5% vs. 6%).
  • A significant portion of infants (76%) did not develop pneumonia post-procedure.

Conclusions:

  • Laparoscopic Nissen fundoplication is a safe and effective procedure for infants with GERD.
  • Outcomes are comparable to older patients, with a shorter operative duration.
  • The study recommends considering laparoscopic Nissen fundoplication for managing infant GERD due to its low recurrence rate.
Abstract

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