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Laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease in infants
Ling Leung1, Carol Wing Yan Wong, Patrick Ho Yu Chung
1Division of Paediatric Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong.
Insights
Laparoscopic Nissen fundoplication is safe and effective for infants with gastro-oesophageal reflux disease (GERD), showing outcomes comparable to older children. This procedure offers a shorter operative duration and low recurrence rates for infant GERD management.
Area of Science:
- Pediatric Surgery
- Gastroenterology
Background:
- Limited data exists on laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease (GERD) in infants.
- This study describes the experience with this procedure in children, focusing on infants under 12 months.
Purpose of the Study:
- To evaluate the safety and efficacy of laparoscopic Nissen fundoplication in infants compared to older children.
- To assess surgical outcomes, including operative time, complications, and recurrence rates.
Main Methods:
- Retrospective review of paediatric patients who underwent laparoscopic fundoplication for GERD between 1998 and 2013.
- Patients were divided into two groups: infants (0-12 months) and older children (>12 months).
- Data collected included indications, demographics, operative time, blood loss, conversions, complications, recurrences, and hospitalization duration.
Main Results:
- 86 patients were reviewed (21 infants, 65 older children).
- Operative time was shorter in infants (157 min vs. 169 min).
- Surgical outcomes were comparable between groups, with low recurrence (0% vs. 3%) and complication rates (9.5% vs. 6%).
- A significant portion of infants (76%) did not develop pneumonia post-procedure.
Conclusions:
- Laparoscopic Nissen fundoplication is a safe and effective procedure for infants with GERD.
- Outcomes are comparable to older patients, with a shorter operative duration.
- The study recommends considering laparoscopic Nissen fundoplication for managing infant GERD due to its low recurrence rate.
Introduction:
Data on laparoscopic Nissen fundoplication for gastro-oesophageal reflux disease (GERD) in infants remain limited. We describe our experience with this operation in children and in particular, infants younger than 12 months old.
Materials And Methods:
Medical records of all paediatric patients who had laparoscopic fundoplication done for GERD from 1998 to 2013 were reviewed. Patients were divided into two groups based on age: group I: 0-12 months, and group II >12 months. Data on indications, patient's demographics, operative time, blood loss, conversions, complications, recurrences and duration of hospitalization were studied.
Results:
A total of 86 patients were reviewed (group I, n = 21; group II, n = 65). While the mean age and body weight for group I were 8 ± 2.99 months and 6 ± 1.96 kg, the values for group II were 98 ± 65 months and 18 ± 9.6 kg, respectively. All patients had concurrent laparoscopic gastrostomy for feeding difficulties. The mean operative time was shorter in group I (157 ± 55 vs 169 ± 52 min, p = 0.66). Both groups had minimal blood loss only. The surgical outcomes in both groups were comparable in terms of recurrence (0 vs 3 %, p = 0.105) and complications (9.5 vs 6 %, p = 0.275). The median follow-up duration for group I and group II was 23 and 40 months, respectively. Sixteen (76 %) patients in group I and 45 (67 %) patients in group II did not develop pneumonia post fundoplication.
Conclusion:
Laparoscopic Nissen fundoplication can be safely performed in infants with outcomes comparable to older patients and a shorter operative duration. Low recurrence rate (up to 3 %) is shown by our long term follow-up data. We recommend laparoscopic Nissen fundoplication to be considered in managing infants with GERD.
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