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Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid Moiety

Shuwen He1, Qingmei Hong1, Zhong Lai1

  • 1Early Development and Discovery Sciences, Merck Research Laboratories , 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.

ACS Medicinal Chemistry Letters
|October 29, 2014
PubMed

Keywords:
A2A receptorACAT1Ames testDGAT1benzimidazolecyclohexanecarboxylic acidepimerizationinhibitorlipid tolerance testmetaboliteskin

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