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Effects of medication methods after simple and effective probing of lacrimal passage
Bin Lu1, Hua-Ying Xie1, Cai-Ping Shi1
1Department of Ophthalmology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, China.
Insights
Reducing oral antibiotics after infant bacterial dacryocystitis probing is effective. This study found that ophthalmic antibiotics alone provide a simple and safe treatment, achieving similar cure rates to combined therapies.
Area of Science:
- Ophthalmology
- Pediatrics
- Infectious Diseases
Background:
- Bacterial dacryocystitis is a common infection in infants.
- Nasolacrimal duct probing is a standard treatment for persistent cases.
- The role of postoperative antibiotic use requires further clarification.
Purpose of the Study:
- To evaluate the efficacy of reducing antibiotic use in infant bacterial dacryocystitis treatment post-nasolacrimal duct probing.
- To compare outcomes between topical and oral antibiotic regimens after surgical intervention.
Main Methods:
- A cohort of 542 infants undergoing nasolacrimal duct probing was divided into two groups: topical antibiotics vs. topical and oral antibiotics.
- Bacterial infection was monitored via conjunctival sac secretions.
- Treatment success was assessed by epiphora symptom resolution and lacrimal passage patency.
Main Results:
- No significant differences were observed between the groups regarding gender, age, or postoperative infection control.
- Cure rates after three probing procedures were comparable across both treatment groups.
- Topical antibiotic treatment alone demonstrated similar efficacy to combined topical and oral antibiotic use.
Conclusions:
- Postoperative treatment with ophthalmic antibiotics alone is a simple, effective, and safe method for infant bacterial dacryocystitis after lacrimal duct probing.
- Reducing the use of oral antibiotics in this context does not compromise treatment outcomes.
- This approach simplifies postoperative care and potentially reduces antibiotic resistance.
Aim:
To evaluate the effect of reducing the use of antibiotics in the treatment of infant bacterial dacryocystitis after probing of the lacrimal duct.
Methods:
A total of 542 cases of children under one year old and accepting nasolacrimal duct probing treatment were divided into two groups, which were treated with topical and oral antibiotics, respectively. Conjunctival sac secretions were used as a control index of bacterial infection, whereas the disappearance of epiphora symptoms and lacrimal passage patency were used as cure indexes. The χ (2) test was used to compare enumeration and measurement data, and a statistical significance was set at P<0.05. The therapeutic effect on the two groups of postoperative patients was investigated.
Results:
In the two study groups, no significant differences in gender, age and postoperative control of lacrimal sac infection were observed. The cure rates after three probing operations also showed no significant difference.
Conclusion:
After probing of the lacrimal passage, results of this study confirmed that postoperative medication without oral antibiotics but an ophthalmic dosage of antibiotics was a simple and effective treatment method.
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