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Probing structural changes of self assembled i-motif DNA

Il Joon Lee1, Sachin P Patil, Karim Fhayli

  • 1Controlled Release and Delivery Lab (CRD), Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Makkah 23955-6900, Kingdom of Saudi Arabia. niveen.khashab@kaust.edu.sa.

Chemical Communications (Cambridge, England)
|October 29, 2014
PubMed
Summary

We developed a novel fluorescent sensor using Thioflavin T (ThT) to detect i-motif DNA structures. This system effectively distinguishes structural changes in RET and Rb i-motif sequences based on pH variations.

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