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Related Experiment Video

Updated: Apr 21, 2026

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Synthesis of Metal Nanoparticles Supported on Carbon Nanotube with Doped Co and N Atoms and its Catalytic Applications in Hydrogen Production

Published on: December 6, 2021

Artificial concurrent catalytic processes involving enzymes.

Valentin Köhler¹, Nicholas J Turner

¹Department of Chemistry, University of Basel, Spitalststrasse 51, CH-4056 Basel, Switzerland. valentin.koehler@unibas.ch.

Chemical Communications (Cambridge, England)

|October 29, 2014

Summary

This summary is machine-generated.

Concurrent cascade catalysis combines multiple catalysts, including enzymes and transition metals, for efficient multi-step reactions. This review highlights recent advances in combining biocatalysis and metal catalysis for complex chemical transformations.

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Area of Science:

Catalysis
Biocatalysis
Organometallic Chemistry

Background:

Concurrent cascade catalysis enables complex transformations through multi-catalyst systems.
Enzymes offer high compatibility for biocatalytic processes, enabling engineered whole-cell or in vitro applications.
Enzyme variants and metalloenzymes expand substrate scope, selectivity, and reactivity.

Purpose of the Study:

To review recent advancements in concurrent cascade catalysis.
To emphasize the synergistic combination of transition metal and enzymatic catalysis.
To encourage further research in this emerging field.

Main Methods:

Co-expression of enzyme genes for pathway reconstruction.
In vitro combination of isolated enzymes.
Integration of transition metal catalysts with enzymatic systems.
Development of engineered whole-cell biocatalysts.

Main Results:

Demonstration of simultaneous multi-step transformations.
Control over intermediate equilibria and stereoconvergent outcomes.
Efficient processing of labile reaction products.
Established cascades for cofactor regeneration and co-product removal.

Conclusions:

Concurrent cascade catalysis offers enhanced reaction features and efficiency.
The combination of transition metal and enzymatic catalysis is a promising area.
Further exploration of concurrent cascade catalysis is encouraged for novel applications.