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Updated: Apr 21, 2026

Direct Mouse Trauma/Burn Model of Heterotopic Ossification
Published on: August 6, 2015
[Calcified bowel mesentery - heterotopic mesenteric ossification]
Nikolaj Nerup1, Philip Hansen, Peter Gocht-Jensen
1Gastroenheden, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev. nikolajnerup@gmail.com.
Heterotopic mesenteric ossification, an extremely rare condition, can develop after abdominal trauma and surgery. This case highlights the potential for extensive calcification in the bowel mesentery, suggesting conservative management is preferred.
Area of Science:
- Gastroenterology
- Abdominal Surgery
- Pathology
Background:
- Blunt abdominal trauma can lead to serious complications like ischemic colon.
- Surgical intervention, such as colectomy with primary anastomosis, may be required for ischemic colon.
- Anastomotic leakage is a potential complication following bowel surgery, necessitating temporary stoma creation.
Observation:
- A 64-year-old male presented with complications following blunt abdominal trauma and subsequent colectomy.
- Extensive calcification of the bowel mesentery was discovered during planned stoma reversal six months post-surgery.
- This calcification represented a rare condition known as heterotopic mesenteric ossification.
Findings:
- Heterotopic mesenteric ossification is an exceptionally rare condition with an unknown pathogenesis.
- The condition is potentially associated with mesenteric ischemia, generalized peritonitis, or abdominal trauma.
- Surgical intervention may exacerbate or trigger further ossification, indicating a need for conservative treatment.
Implications:
- This case underscores the importance of recognizing heterotopic mesenteric ossification in patients with a history of abdominal trauma and surgery.
- Conservative management is recommended to avoid precipitating further ossification.
- Further research into the pathogenesis of heterotopic mesenteric ossification is warranted to guide future treatment strategies.
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