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TOX2 regulates human natural killer cell development by controlling T-BET expression

Queenie P Vong1, Wai-Hang Leung1, Jim Houston1

  • 1Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, TN;

Blood
|October 30, 2014
PubMed
Summary

TOX2 is crucial for natural killer (NK) cell development in humans. This transcription factor enhances NK cell maturation by regulating T-BET, essential for NK cell differentiation.

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