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Updated: Apr 21, 2026

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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
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Simple text-messaging intervention is associated with improved door-to-needle times for acute ischemic stroke
Molly M Burnett1, Lara Zimmermann1, Zlatan Coralic1
1From the Departments of Neurology (M.M.B., L.Z., A.S.K.), Emergency Medicine (T.Q., W.W.), and Clinical Pharmacy (Z.C.), University of California, San Francisco.
Stroke
|October 30, 2014
Summary
A text-messaging intervention significantly reduced door-to-needle times for acute ischemic stroke treatment. This quality improvement initiative improved timeliness of care, leading to better patient outcomes with intravenous tissue-type plasminogen activator.
Area of Science:
- Neurology
- Quality Improvement Science
- Health Informatics
Background:
- Timely administration of intravenous tissue-type plasminogen activator (IV tPA) is critical for acute ischemic stroke outcomes.
- Consistent and prompt treatment delivery for stroke remains a significant clinical challenge.
- Developing effective quality improvement interventions is essential for optimizing stroke care pathways.
Purpose of the Study:
- To develop and evaluate a quality improvement intervention aimed at reducing door-to-needle (DTN) times.
- To assess the impact of a text-messaging based intervention on the timeliness of IV tPA administration.
- To improve resident-led Code Stroke team performance at an academic medical center.
Main Methods:
- A simple text-messaging intervention with real-time feedback was implemented.
- The intervention targeted door-to-needle times for patients receiving IV tPA.
- Statistical analysis using rank-sum test and linear regression evaluated changes in DTN times.
Main Results:
- The study included 202 patients (94 preintervention, 108 postintervention).
- Median DTN time significantly decreased from 82 minutes to 56 minutes postintervention (P<0.0001).
- The proportion of patients treated within 60 minutes increased from 16% to 61% (P<0.001).
Conclusions:
- A simple, real-time text-messaging intervention effectively improved DTN times for acute ischemic stroke.
- This quality improvement strategy demonstrates a significant positive impact on stroke treatment efficiency.
- The intervention offers a scalable solution for enhancing acute stroke care delivery.

