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Fatal fungal infection: the living dead
Sankar Narayanan Ml1, C D Narayanan2, Anupma J Kindo3
1Department of General Surgery, SRMC, Chennai, India shanki_vl87@yahoo.co.in.
Abstract:
Necrotizing fasciitis is an uncommon infection mainly caused by Streptococcus pyogenes, which is also known as flesh-eating bacteria. It is often caused by bacteria, but can also be caused and complicated by fungus. We report a case of bacterial necrotizing fasciitis that was complicated by a fatal fungal infection, a rare clinical presentation affecting the upper limbs, head and neck, in a young diabetic female patient. It was an unsuspected case of fungal infection with mucormycosis, which proved to be fatal due to a delay in diagnosis and treatment.
Insights
Necrotizing fasciitis, a severe infection, can be complicated by fungal infections like mucormycosis. This case highlights a fatal outcome in a diabetic patient due to delayed diagnosis and treatment.
Area of Science:
- Infectious Diseases
- Mycology
- Dermatology
Background:
- Necrotizing fasciitis is a severe bacterial infection, often caused by Streptococcus pyogenes.
- Fungal infections can complicate bacterial necrotizing fasciitis, though rarely.
- Diabetes mellitus is a known risk factor for invasive fungal infections.
Observation:
- A young diabetic female presented with necrotizing fasciitis affecting the upper limbs, head, and neck.
- The bacterial infection was unexpectedly complicated by mucormycosis, a rare fungal pathogen.
- Diagnosis and treatment of the fungal coinfection were delayed.
Findings:
- The case demonstrated a rare progression of necrotizing fasciitis complicated by fatal mucormycosis.
- Delayed diagnosis and treatment of the fungal infection contributed to the fatal outcome.
- The clinical presentation in the upper limbs, head, and neck was unusual for this complication.
Implications:
- Highlights the importance of considering fungal coinfections in severe bacterial infections, especially in immunocompromised patients.
- Emphasizes the critical need for prompt diagnosis and multidisciplinary management of necrotizing fasciitis and its complications.
- Underscores the potential severity of mucormycosis in diabetic patients, necessitating increased clinical vigilance.
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