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Related Concept Videos

Diabetic Neuropathy01:22

Diabetic Neuropathy

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DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Arboviral Encephalitis01:25

Arboviral Encephalitis

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Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
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Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

802
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
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Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

676
 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
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Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

653
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
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Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
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Asymptomatic vasculitic neuropathy.

Semiha Kurt1,2, Mohammad Alsharabati1, Liang Lu1

  • 1Department of Neurology, University of Alabama at Birmingham, UAB Station, Birmingham, Alabama, 35294, USA.

Muscle & Nerve
|October 30, 2014
PubMed
Summary
This summary is machine-generated.

Asymptomatic vasculitic neuropathy (AsVN) is a subtype of vasculitic neuropathy. Nerve conduction studies are crucial for diagnosing AsVN, even when symptoms are absent.

Keywords:
asymptomaticnerve conduction studyneuropathyvasculitic neuropathyvasculitis

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Area of Science:

  • Neurology
  • Immunology
  • Pathology

Background:

  • Vasculitic neuropathy (VN) is a rare condition.
  • Asymptomatic vasculitic neuropathy (AsVN) is a subtype of VN.
  • This study analyzed 21 cases of AsVN.

Purpose of the Study:

  • To investigate the clinical, pathological, and electrophysiological characteristics of AsVN.
  • To highlight the diagnostic utility of nerve conduction studies in AsVN.

Main Methods:

  • Retrospective analysis of 270 patients with biopsy-proven VN.
  • Identification of 21 patients (7.8%) with AsVN.
  • Review of clinical, pathological, and electrophysiological data.

Main Results:

  • The study included 11 women and 10 men with a mean age of 62.5 years.
  • No patients presented with neuropathy on physical examination.
  • Nerve conduction studies detected neuropathy in all cases, confirmed by sural nerve biopsy.

Conclusions:

  • Nerve conduction studies are essential for identifying AsVN.
  • AsVN is a distinct subtype of vasculitic neuropathy that may be missed without electrophysiological testing.