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A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
Published on: July 12, 2021
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[Complex febrile crises: should we change the way we act?]
E Martinez-Cayuelas1, M Herraiz-Martinez, L Villacieros-Hernandez
1Hospital Universitario Virgen de la Arrixaca, El Palmar, Espana.
Revista De Neurologia
|October 31, 2014
Summary
Complex febrile seizures (CFS) in children do not typically lead to acute complications. Hospitalization for CFS may be unnecessary unless other clinical signs are present, suggesting a less invasive approach.
Area of Science:
- Neurology
- Pediatrics
- Clinical Medicine
Background:
- Febrile seizures are a common reason for pediatric healthcare visits.
- Historically, complex febrile seizures (CFS) necessitated hospitalization due to perceived risks of epilepsy and complications.
- Emerging evidence suggests a less invasive management approach for CFS is feasible.
Purpose of the Study:
- To characterize patients hospitalized for CFS.
- To propose an updated protocol for managing CFS cases.
Main Methods:
- Retrospective analysis of medical records for hospitalized CFS patients (Jan 2010-Dec 2013).
- Collection and presentation of epidemiological, clinical, and follow-up data.
- Evaluation of the diagnostic utility of complementary tests during the acute phase.
Main Results:
- CFS represented 4.2% of pediatric neurology admissions (67 patients).
- Mean age was 25 months; 47% had a family history, and 31% had prior febrile seizures.
- Most CFS events were brief (<5 min) and recurrent, often within the first day. Diagnostic tests were not useful acutely. Five patients had complications during follow-up. Family history correlated with higher epilepsy/recurrence risk (p=0.02).
Conclusions:
- CFS are not linked to increased acute complications.
- Current complementary examinations do not reliably identify high-risk patients early.
- Hospitalization for CFS could be avoided in most cases, reserving it for those with additional clinical signs.
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