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Pulmonary pyoderma gangrenosum without cutaneous manifestations.
Kenneth Kazuto Sakata1, Sudheer Penupolu1, Thomas Vail Colby2
1Department of Internal Medicine, Division of Pulmonary Medicine, Mayo Clinic Arizona, Scottsdale, AZ, USA.
The Clinical Respiratory Journal
|October 31, 2014
Summary
This case report details a rare instance of pulmonary pyoderma gangrenosum presenting before skin symptoms and without systemic disease. Early diagnosis and corticosteroid treatment led to patient recovery.
Area of Science:
- Pulmonary Medicine
- Dermatology
- Pathology
Background:
- Pyoderma gangrenosum (PG) is a chronic sterile neutrophilic dermatosis.
- It often associates with systemic conditions like inflammatory bowel disease.
- Extracutaneous PG is rare, typically affecting the lungs.
Observation:
- A 19-year-old male presented with respiratory symptoms (shortness of breath, cough).
- Initial skin examination revealed no lesions.
- Chest CT showed consolidations, cavitation, nodules, and pleural effusions.
Findings:
- Bronchoalveolar lavage and autoimmune panel were unremarkable.
- Lung biopsies confirmed pulmonary pyoderma gangrenosum.
- This is the first reported case of pulmonary PG without cutaneous or systemic manifestations.
Implications:
- Highlights the possibility of primary pulmonary pyoderma gangrenosum.
- Emphasizes the need for vigilant follow-up for potential systemic or cutaneous disease development.
- Corticosteroid therapy proved effective in this unique presentation.
Keywords:
extracutaneous pyoderma gangrenosumgranulomatosis with polyangiitisinflammatory bowel diseasepulmonary pyoderma gangrenosumMore Related Videos
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