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Standard compounds for establishment of in vitro test systems

J G Hengstler1, R Marchan, H M Bolt

  • 1Leibniz Research Centre for Working Environment and Human Factors (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany, hengstler@ifado.de.

Archives of Toxicology
|October 31, 2014
PubMed
Summary

No abstract available in PubMed .

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Compendial dissolution methods are standardized procedures defined by pharmacopeias to evaluate the rate at which a drug dissolves in a specific medium. These methods ensure batch-to-batch consistency, enable quality control, and support the prediction of drug bioavailability. They are critical for both immediate and modified-release drug products.The apparatuses used for dissolution testing differ in their design and mechanical function, but all aim to simulate the physiological environment of...
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