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Descriptive Epidemiology in Mexican children with cancer under an open national public health insurance program
Roberto Rivera-Luna1, Jaime Shalkow-Klincovstein, Liliana Velasco-Hidalgo
1Head of the Division of Pediatric Hem/Oncology, National Institute of Pediatrics (NIP), Coordinator for the Technical Committee of the National Council for the Prevention and Treatment of Childhood Cancer, Mexico City, Mexico. riveraluna@terra.com.mx.
Insights
Childhood cancer incidence in Mexico is high, with leukemia being the most common. A national program has improved treatment outcomes for pediatric cancer patients, with low abandonment rates.
Area of Science:
- Pediatric Oncology
- Public Health
- Epidemiology
Background:
- Analysis of children registered with the National Council for the Prevention and Treatment of Childhood Cancer in Mexico.
- The program provides financial support for treatment across 55 public hospitals nationwide.
Purpose of the Study:
- To analyze the prevalence, incidence, mortality, and abandonment rates of childhood cancers in Mexico.
- To evaluate the impact of a national program on pediatric cancer treatment outcomes.
Main Methods:
- Retrospective analysis of data from 2007-2012 for patients aged 0-18 years.
- Inclusion of pathological diagnoses of leukemia, lymphoma, and solid tumors.
- Analysis of key epidemiological parameters including incidence, prevalence, mortality, and treatment abandonment.
Main Results:
- 14,178 childhood cancer cases documented.
- Overall incidence: 156.9/million/year (2012). Leukemia is the most common cancer (49.8% of cases).
- National mortality rate: 5.3/100,000 (2012), with higher rates in adolescents (15-18 years).
Conclusions:
- High incidence of childhood cancer in Mexico, particularly leukemia in children aged 0-4 years.
- Low treatment abandonment rate (4.7%).
- Significant improvement in clinical outcomes for pediatric cancer patients since the program's inception.
Background:
All the children registered at the National Council for the Prevention and Treatment of Childhood Cancer were analyzed. The rationale for this Federal Government Council is to financially support the treatment of all children registered into this system. All patients are within a network of 55 public certified hospitals nationwide.
Methods:
In the current study, data from 2007 to 2012 are presented for all patients (0-18 years) with a pathological diagnosis of leukemia, lymphoma and solid tumors. The parameters analyzed were prevalence, incidence, mortality, and abandonment rate.
Results:
A diagnosis of cancer was documented in 14,178 children. The incidence was of 156.9/million/year (2012). The median age was 4.9. The most common childhood cancer is leukemia, which occurs in 49.8% of patients (2007-2012); and has an incidence rate of 78.1/million/year (2012). The national mortality rate was 5.3/100,000 in 2012, however in the group between 15 to 18 years it reaches a level of 8.6.
Conclusions:
The study demonstrates that there is a high incidence of childhood cancer in Mexico. In particular, the results reveal an elevated incidence and prevalence of leukemia especially from 0 to 4 years. Only 4.7% of these patients abandoned treatment. The clinical outcome for all of the children studied improved since the establishment of this national program.
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