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Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
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Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

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Genital tract microbial isolate in women with preterm pre-labour rupture of membranes in resource-constrained

G U Eleje1, J I Adinma1, D C Ugwuanyi2

  • 1a Department of Obstetrics and Gynecology , Nnamdi Azikiwe University, Teaching Hospital , Nnewi , Nigeria.

Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology
|October 31, 2014
PubMed

This study determined patterns of microbial isolates in genital tract of women with preterm pre-labour rupture of membranes (PPROM) compared with cases without PPROM. Endocervical swabs of women with confirmed diagnosis of PPROM were examined microbiologically and compared in blinded pattern with gestational-age-matched controls. One hundred and five microbiological results each for cases and controls were analysed. Positive microbial cultures were seen in 79.05% of cases versus 6.67% of controls. Streptococcus spp. (31.43%) was the commonest organism isolated in cases (p < 0.001), while Candida albicans was significantly more in controls (p < 0.001). The highest incidence of PPROM (82.86%) occurred in gestational ages of 28-30 and 34-36 weeks. No fewer than 75.24% cases occurred in low parity (0-2). Majority occurred in extremes of viable preterm gestation and in women of low parity.

Keywords:
ControlsPPROMendocervical swabsmicrobial agentspositive cultures

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