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Bilateral maculopathy associated with sertraline.

Shaun Y P Ewe1, Robin G Abell2, Brendan J Vote3

  • 1Tasmanian Eye Institute, Ophthalmology Registrar & Clinical Research Fellow, South Launceston, TAS, Australia shaunewe@gmail.com.

Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists
|November 1, 2014
PubMed
Summary
This summary is machine-generated.

A rare case of bilateral maculopathy, a vision impairment, developed in a young man after starting sertraline. Discontinuation of sertraline led to mild visual improvement, suggesting a potential adverse effect.

Keywords:
drug-inducedmaculopathyocular toxicityselective serotonin reuptake inhibitorsertraline

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Area of Science:

  • Ophthalmology
  • Pharmacology
  • Neuroscience

Background:

  • Selective serotonin reuptake inhibitors (SSRIs) like sertraline are commonly prescribed for depression and anxiety.
  • Ocular side effects of SSRIs are infrequently reported, with maculopathy being exceptionally rare.

Observation:

  • A 23-year-old male presented with bilateral maculopathy and blurred vision shortly after initiating sertraline treatment.
  • The patient's visual symptoms showed mild improvement upon cessation of the medication.

Findings:

  • This case highlights a potential association between sertraline and the development of maculopathy.
  • The rarity of this condition suggests it may be an idiosyncratic or underreported adverse drug reaction.

Implications:

  • Further investigation is warranted to establish maculopathy as a recognized adverse effect of sertraline.
  • Increased clinical awareness among ophthalmologists and psychiatrists is crucial for early detection and management.