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Limb hypoplasia resulting from intrauterine infection with herpes simplex virus: a case report

D Carola1, M Skibo1, S Cannon2

  • 1Division of Neonatology, Nemours at Thomas Jefferson University, Philadelphia, PA, USA.

Journal of Perinatology : Official Journal of the California Perinatal Association
|November 1, 2014
PubMed

Intrauterine infection with herpes simplex virus, although very rare, has devastating effects on multiple organ systems in the fetus and can lead to in utero fetal demise. Neonates born following intrauterine herpes simplex virus infection commonly manifest with cutaneous lesions, ocular damage and/or brain abnormalities. We describe the case of a dichorionic, diamniotic twin gestation complicated by intrauterine herpes simplex virus infection. This infection led to the fetal demise of twin A and a very uncommon presentation of limb hypoplasia in twin B.

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