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Light-mediated antibacterial activity of Lippia origanoides H.B.K. in vitro
Humberto M Barreto1, Bruno R C Coelho, Suellen M P Menezes-Silva
1Laboratory of Research in Microbiology, Department of Parasitology and Microbiology, Federal University of Piauí, Teresina (PI), Brazil.
Abstract:
An ethanol extract and different partition fractions obtained from Lippia origanoides H.B.K. were assayed for light-mediated activity against strains of Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). Identical assays were conducted with and without exposure to UV-A (400-315 nm) light to test for light enhanced activity. The ethanol extract and dichloromethane fraction showed light-mediated activity against the S. aureus strain, but not against the E. coli strain. The dichloromethane fraction was more active than the ethanol extract. Naringenin did not display light-mediated activity against the tested bacteria, indicating that the light-mediated antimicrobial activity of the dichloromethane fraction is not due to its major component. The results represent the first report of light-mediated antimicrobial activity of Lippia origanoides and show that its phytochemicals could be used as light-mediated antimicrobial agents.
