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PCR-based national bacterial meningitis surveillance in Turkey: years 2006 to 2009
Demet Toprak1, Ahmet Soysal, Mehmet Ali Torunoğlu
1From the *Boston Children's Hospital, Harvard Medical School, Department of Medicine, Division of Pulmonary Medicine; †Department of Pediatrics, Division of Pediatric Infectious Diseases, Marmara University School of Medicine, Istanbul, Turkey; ‡Department of Infectious Diseases, Turkish Ministry of Health; §Department of Pediatrics, Adıyaman University Medical Faculty, Adıyaman, Turkey; ¶Department of Microbiology, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey; ‖Streptococcus Laboratory, Respiratory Diseases Branch, Centers for Disease Control and Prevention; **Meningitis Laboratory, Meningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention; ††Department of Clinical Microbiology, Marmara University School of Medicine; and ‡‡Department of Clinical Microbiology, Istanbul University Cerrahpaşa School of Medicine, Istanbul, Turkey.
Abstract:
Polymerase chain reaction-based surveillance for bacterial meningitis including 841 children revealed 246 with bacterial DNA in cerebrospinal fluid samples of which 53% were Streptococcus pneumoniae, 19% Neisseria meningitidis, and 16% Haemophilus influenzae type b. The most common S. pneumoniae serotypes/serogroups were 1, 19F, 6A/6B, 23F, 5, 14, 18 and 19A. Among 47 meningococci, 86% were serogroup B, 6% serogroup C, 3% serogroup A, 3% serogroup X and 3% serogroup W.
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