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Related Concept Videos

Clipper Circuit01:18

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A clipper circuit is a fundamental wave-shaping device that harnesses the unique properties of diodes to alter and control waveform characteristics. This technology is widely used in electronic devices, especially in television and radar communication systems, where it enhances waveform modulation in both transmitters and receivers.
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Fast Decoupled and DC Powerflow01:24

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Related Experiment Video

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The Xenopus Oocyte Cut-open Vaseline Gap Voltage-clamp Technique With Fluorometry
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DC current pulses for OTSC clip fragmentation: technology and experimental study.

Sebastian Schostek1, C N Ho, M Melbert

  • 1Division Diagnostic Systems, Ovesco Endoscopy AG, Dorfackerstr. 26, 72074, Tuebingen, Germany, sebastian.schostek@ovesco.com.

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|November 2, 2014
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Summary
This summary is machine-generated.

This study demonstrates a novel endoscopic technique to safely remove over-the-scope clips (OTSCs) by melting them with electrical pulses. The method proved effective in a porcine model, with fragments safely extracted using a specialized cap.

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Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Medical Device Development

Background:

  • Over-the-scope clips (OTSCs) are utilized for gastrointestinal lesion management.
  • Rare instances necessitate OTSC clip removal.
  • A novel endoscopic system for OTSC clip removal was investigated.

Purpose of the Study:

  • To assess the feasibility, efficacy, and safety of a new endoscopic instrument for OTSC clip removal.
  • To evaluate a prototype system designed to melt and extract OTSC clips.

Main Methods:

  • The study employed a porcine model (n=10) for evaluation.
  • A prototype instrument applied electrical current pulses to melt OTSC clips.
  • An elongated sleeve cap prototype facilitated OTSC clip fragment extraction.

Main Results:

  • Successfully opened 23 out of 24 implanted OTSC clips using electrical pulses.
  • Observed superficial mucosal coagulation marks in 14 sites.
  • No significant adverse events like hemorrhage or perforation occurred.

Conclusions:

  • The endoscopic removal technique is effective and safe.
  • Extraction of OTSC clip fragments using an elongated sleeve cap is feasible.
  • Limitations include the use of an animal model and prototype instrumentation.