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Published on: January 20, 2022
Genenames.org: the HGNC resources in 2015
Kristian A Gray1, Bethan Yates1, Ruth L Seal1
1HUGO Gene Nomenclature Committee, European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
The HUGO Gene Nomenclature Committee (HGNC) has expanded its human gene database to over 39,000 entries. Recent updates to the genenames.org website improve data access and search functionality for researchers.
Area of Science:
- Genomics
- Bioinformatics
- Human Genetics
Background:
- The HUGO Gene Nomenclature Committee (HGNC) is responsible for assigning standardized nomenclature to human genes.
- Accurate gene symbols and names are crucial for clear communication in genetic research.
Purpose of the Study:
- To provide an overview of the current human gene data and resources available through the HGNC.
- To highlight recent improvements and updates to the HGNC website (genenames.org).
Main Methods:
- Database expansion with over 5000 new gene entries in two years.
- Redesign of the genenames.org website.
- Implementation of a faster search, improved HCOP tool, and a REST service.
Main Results:
- The HGNC database now contains over 39,000 human gene symbols and names.
- Significant enhancements to the genenames.org website improve user experience and data retrieval.
- New tools and services facilitate broader access to gene nomenclature data.
Conclusions:
- The HGNC continues to be a vital resource for human gene identification and standardization.
- Ongoing website development ensures efficient access to up-to-date gene information.
- These advancements support the global genomics research community.
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